Can a rational design for metronomic chemotherapy dosing be devised?

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Metronomic Chemotherapy: When Less May Be More

The use of low dose continuous schedules of chemotherapy (i.e. metronomic chemotherapy), delivered at lower doses by necessity compared to traditional dosing schemes, has become an increasingly popular addition to patient management in veterinary medical oncology. While the concept itself is not new, as low dose, maintenance chemotherapy protocols have been important components of treatment for...

متن کامل

Can metronomic chemotherapy be an alternative to sorafenib in advanced hepatocellular carcinoma?

Conventional hepatic arterial infusion chemotherapy (HAIC), consisting of 5-fluorouracil (5-FU) and cisplatin delivered via implanted chemoport every 4 weeks, is a form of regional to systemic chemotherapy to treat unresectable or advanced hepatocellular carcinoma (HCC). The idea of localized infusion of cytotoxic agents into liver originated from hepatic metastasis of colorectal cancer. It is ...

متن کامل

“Dysfunctional Identities” Can Be Rational

Understanding the nature and sources of human identity is an important objective in the study of a variety of social problems. Scholarly and popular writing on the cultural determinants of economic disadvantage underscores this point. Some analysts (e.g., Edward Banfield 1970, Thomas Sowell 1994, John McWhorter 2000, and John Ogbu 2003, to name a varied few) have hypothesized that a causal conn...

متن کامل

Antiangiogenic metronomic chemotherapy.

Accessible online at: www.karger.com/onk Fax +49 761 4 52 07 14 E-mail [email protected] www.karger.com Most of the phase I–II clinical studies performed up to now used ‘metronomic-like’ schedules of cytostatic agents, often administered using weekly schedules of vinca alkaloids, taxanes, anthracyclines or alkylating agents resulting, however, in high dose-density treatments. A rational ide...

متن کامل

Can targeted therapy be successful without metronomic scheduling?

In medical oncology, targeted therapy has emerged over the last decade, as the most promising strategy to fight cancer. In addition, a more complete understanding of tumor heterogeneity and pharmacology of the more conventional anti-cancer agents has led to development of metronomic chemotherapy (MC) (i.e. a more frequent administration of anticancer agents at lower doses then the usual maximal...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: British Journal of Cancer

سال: 2005

ISSN: 0007-0920,1532-1827

DOI: 10.1038/sj.bjc.6602474